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Source: http://www.msnbc.msn.com/id/29054368/vp/46190362#46190362
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Tuesday, January 31, 2012
Monday, January 30, 2012
Genetic regulation of metabolomic biomarkers - paths to cardiovascular diseases and type 2 diabetes
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Public release date: 29-Jan-2012[ | E-mail |
Share ] Contact: Dr. Samuli Ripatti
samuli.ripatti@fimm.fi
358-206-108-159
University of Helsinki
In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body. Many of the studied metabolites are biomarkers for cardiovascular disease or related disorders, thus the loci uncovered may provide valuable insight into the biological processes leading to common diseases.
Laboratory tests used in the clinic typically monitor one or few circulating metabolites. The researchers at the Institute for Molecular Medicine Finland (FIMM) used a high throughput method called nuclear magnetic resonance (NMR) that can measure more than hundred different metabolites in one assay. This provides a much more in-depth picture of circulating metabolic compounds.
"Using this extensive analysis in thousands of people, we could identify a large number of genetic loci regulating the level of compounds circulating in the blood stream", says Dr. Samuli Ripatti, the leader of the study.
The team assayed 117 detailed metabolic markers, including lipoprotein subclasses, amino acids and lipids, and conducted the largest genome-wide association analysis of this type, in terms of study sample size of 8330 individuals from six Finnish population-based cohorts and 7.7 million genomic markers studied. They revealed, in total, 31 genetic regions associated with the blood levels of the metabolites.
Eleven of the loci had not been previously shown to be associated with any metabolic measures.
Among the findings were two new loci affecting serum cholesterol subclass measures, well-established risk markers for cardiovascular disease, and five new loci affecting levels of amino acids recently discovered to be potential biomarkers for type 2 diabetes. The discovered variants have significant effects on the metabolite levels, the effect sizes being in general considerably larger than the known common variants for complex disease have.
Also, using Finnish twin pair samples, the researchers indicated that the metabolite levels show a high degree of heritability. "This result suggests that the studied metabolites are describing better the underlying biology than the routinely used laboratory tests. Therefore, the study provides further support for the use of detailed data on multitude of metabolites in genetic studies to provide novel biological insights and to help in elucidating the processes leading to common diseases", Dr. Ripatti says.
###
Dr. Samuli Ripatti is a FIMM-EMBL Group Leader at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland (http://www.fimm.fi) and a Honorary Faculty Member at the Wellcome Trust Sanger Institute, UK (http://www.sanger.ac.uk)
The Institute for Molecular Medicine Finland FIMM is an international research institute focusing on building a bridge from discovery to medical applications. FIMM investigates molecular mechanisms of disease using genomics and medical systems biology in order to promote human health. FIMM is a multi-disciplinary institute combining high-quality science with unique research cohorts and patient materials, and state-of-the-art technologies. Website http://www.fimm.fi
The Wellcome Trust Sanger Institute is one of the world's leading genome centres. Through its ability to conduct research at scale, it is able to engage in bold and long-term exploratory projects that are designed to influence and empower medical science globally. Institute research findings, generated through its own research programmes and through its leading role in international consortia, are being used to develop new diagnostics and treatments for human disease. Website http://www.sanger.ac.uk/
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 29-Jan-2012[ | E-mail |
Share ] Contact: Dr. Samuli Ripatti
samuli.ripatti@fimm.fi
358-206-108-159
University of Helsinki
In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human body. Many of the studied metabolites are biomarkers for cardiovascular disease or related disorders, thus the loci uncovered may provide valuable insight into the biological processes leading to common diseases.
Laboratory tests used in the clinic typically monitor one or few circulating metabolites. The researchers at the Institute for Molecular Medicine Finland (FIMM) used a high throughput method called nuclear magnetic resonance (NMR) that can measure more than hundred different metabolites in one assay. This provides a much more in-depth picture of circulating metabolic compounds.
"Using this extensive analysis in thousands of people, we could identify a large number of genetic loci regulating the level of compounds circulating in the blood stream", says Dr. Samuli Ripatti, the leader of the study.
The team assayed 117 detailed metabolic markers, including lipoprotein subclasses, amino acids and lipids, and conducted the largest genome-wide association analysis of this type, in terms of study sample size of 8330 individuals from six Finnish population-based cohorts and 7.7 million genomic markers studied. They revealed, in total, 31 genetic regions associated with the blood levels of the metabolites.
Eleven of the loci had not been previously shown to be associated with any metabolic measures.
Among the findings were two new loci affecting serum cholesterol subclass measures, well-established risk markers for cardiovascular disease, and five new loci affecting levels of amino acids recently discovered to be potential biomarkers for type 2 diabetes. The discovered variants have significant effects on the metabolite levels, the effect sizes being in general considerably larger than the known common variants for complex disease have.
Also, using Finnish twin pair samples, the researchers indicated that the metabolite levels show a high degree of heritability. "This result suggests that the studied metabolites are describing better the underlying biology than the routinely used laboratory tests. Therefore, the study provides further support for the use of detailed data on multitude of metabolites in genetic studies to provide novel biological insights and to help in elucidating the processes leading to common diseases", Dr. Ripatti says.
###
Dr. Samuli Ripatti is a FIMM-EMBL Group Leader at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland (http://www.fimm.fi) and a Honorary Faculty Member at the Wellcome Trust Sanger Institute, UK (http://www.sanger.ac.uk)
The Institute for Molecular Medicine Finland FIMM is an international research institute focusing on building a bridge from discovery to medical applications. FIMM investigates molecular mechanisms of disease using genomics and medical systems biology in order to promote human health. FIMM is a multi-disciplinary institute combining high-quality science with unique research cohorts and patient materials, and state-of-the-art technologies. Website http://www.fimm.fi
The Wellcome Trust Sanger Institute is one of the world's leading genome centres. Through its ability to conduct research at scale, it is able to engage in bold and long-term exploratory projects that are designed to influence and empower medical science globally. Institute research findings, generated through its own research programmes and through its leading role in international consortia, are being used to develop new diagnostics and treatments for human disease. Website http://www.sanger.ac.uk/
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/uoh-gro012712.php
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Sunday, January 29, 2012
Salvage crews suspend work on capsized ship (Reuters)
GIGLIO, Italy (Reuters) ? Salvage crews preparing to pump thousands of tonnes of diesel fuel and oil from the wreck of the Costa Concordia cruise ship off the Italian coast suspended work on Saturday after heavy seas made conditions unsafe, officials said.
A barge carrying pumping equipment that was attached to the capsized ship was withdrawn although work may be resumed in the afternoon, depending on conditions.
"The wind conditions and waves of more than a meter have forced us to interrupt work but we'll start up again when conditions improve," said Antonino Corsini, one of the emergency services divers working with Dutch salvage company SMIT.
Despite the interruption the search continued for bodies on the half-submerged vessel, which lies in about 20 metres of water on a rock shelf close to the island of Giglio off the Tuscan coast.
Divers found the body of a woman on Saturday, bringing the total number of known dead to 17.
But with no hope of finding survivors, the focus has switched to preventing an environmental disaster in Giglio, a popular holiday island in a marine nature reserve.
Before the work was suspended, crews were installing valves to help pump out six of the ship's fuel tanks, which contain around half of the more than 2,300 tonnes of diesel.
Pumping, originally expected to begin on Saturday, is expected to be delayed until at least Sunday. The process of extracting all the fuel is expected to take at least 28 days, officials have said.
The Concordia, a 290-metre long floating resort carrying more than 4,200 passengers and crew, sank more than two weeks ago after it ran into a rock which tore a hole in its hull.
The accident, expected to create the most expensive maritime insurance claim ever, has triggered a legal battle which has seen U.S. and Italian lawyers preparing class action and individual suits against the operator, Costa Cruises.
In a bid to limit the fallout, Costa, a unit of Carnival Corp, the world's largest cruise ship operator, has offered the more than 3,000 passengers $14,500 each in compensation on condition they drop any legal action.
The Concordia's captain, Francesco Schettino, is under house arrest, suspected of causing the accident by steering too close to shore and faces charges of multiple manslaughter and abandoning ship before the evacuation was complete.
The ship's first officer, Ciro Ambrosio, has also been questioned by prosecutors but the company itself has not been implicated in the investigation at this stage.
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Netanyahu pessimistic on Mideast peace prospects (Reuters)
JERUSALEM (Reuters) ? Peace prospects with the Palestinians are looking poor, Israeli Prime Minister Benjamin Netanyahu said on Sunday after exploratory talks aimed at relaunching negotiations ended in deadlock.
"As things stand now, according to what happened over the past few days - when the Palestinians refused even to discuss Israel's security needs with us - the signs are not particularly good," he told his cabinet in public remarks.
Palestinian officials said last week an Israeli negotiator's verbal presentation on Wednesday of ideas for borders and security arrangements of a future Palestinian state was a non-starter, envisaging a fenced-off territory of cantons that would preserve most Jewish settlements.
Netanyahu said he still hoped the Palestinians would "come to their senses and continue the talks so that we can move on to real negotiations."
Israeli and Palestinian negotiators held five rounds of exploratory talks in Jordan, part of a push by international mediators to revive negotiations suspended in 2010 in a dispute over Jewish settlement building in the occupied West Bank.
A Palestinian source said no more meetings were scheduled. Palestinian President Mahmoud Abbas has said he wants to consult Arab League states on the next move.
An Israeli official said Israel's approach to territorial compromise in the West Bank, captured in the 1967 Middle East war, includes the principle that "most Israelis will be under Israeli sovereignty and obviously most Palestinians will be under Palestinian sovereignty."
The official said Netanyahu had acknowledged, in a speech to the U.S. Congress last May, that not all Jewish settlements "will be on our side of the border" with a future Palestinian state.
The Palestinians want a state in the West Bank and the Gaza Strip with East Jerusalem as its capital. They say Israeli settlements could deny them a viable and contiguous country.
Israel cites biblical and historical ties to the West Bank, an area it calls Judea and Samaria, and says any peace deal must include stringent security arrangements.
(Writing by Jeffrey Heller; editing by Tim Pearce)
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Saturday, January 28, 2012
Panetta cites key intelligence on bin Laden raid (AP)
WASHINGTON ? Defense Secretary Leon Panetta is acknowledging publicly for the first time that a Pakistani doctor provided key information to the U.S. in advance of the successful Navy SEAL assault on Osama bin Laden's compound last May.
Panetta told CBS's "60 Minutes," in a profile to be broadcast on Sunday, that Shakil Afridi helped provide intelligence for the raid on bin Laden's compound in Abbottabad, Pakistan.
Afridi ran a vaccination program for the CIA to collect DNA and verify bin Laden's presence in the compound. He has since been charged by Pakistan with treason. Panetta said he is "very concerned" for the doctor.
Panetta also told "60 Minutes" that he remains convinced that someone in the Pakistani government "must have had some sense" that a person of interest was in the compound. He added that he has no proof that Pakistan knew it was bin Laden.
The Pakistani government had hoped to resolve the Afridi matter quietly, once media attention died down, perhaps releasing him to U.S. custody, according to two Pakistani officials. They requested anonymity because the investigation into charges the doctor behaved treasonously was ongoing.
___
AP Intelligence Writer Kimberly Dozier contributed to this report.
Israeli film industry is a surprising powerhouse
JERUSALEM (AP) ? The budgets are bare-bones and the talent pool is limited, but Israel has emerged as a surprising powerhouse in the foreign film industry.
The Israeli film "Footnote," up for an Academy Award for Best Foreign Language Film this year, is Israel's fourth such nomination in the past five years, giving Israel more nominations during that period than any other country.
It's an indication to the renaissance of Israeli cinema, which has grown from a fledgling industry with poor cinematography and low box office sales to a darling of world film festivals. That's in spite ? or perhaps because ? of the country's troubled international reputation, due to its lengthy conflict with the Arab world.
The last three Israeli films that made it to the Oscar shortlist all mine the country's troubles with its Arab neighbors. "Beaufort," nominated in 2008, and "Waltz with Bashir," nominated a year after, both explored Israeli soldiers' experiences in Lebanon. "Ajami," the 2010 nominee, centers on Arab-Jewish tensions in a violence-ridden neighborhood near Tel Aviv.
This year's nomination went to an Israeli film featuring a more internal conflict ? two professors of Talmud, a father and son, dueling for academic prestige and a coveted national prize.
"It's a badge of honor for Israel," said Moshe Edery, producer of "Footnote," at a news conference after the Oscar nomination. "It's Israel's best business card around the world, especially these days."
Israeli cinema was long an embarrassment. Cheap comic melodramas were the norm in the 1960s and 1970s. Called "bourekas films" ? the Israeli equivalent of spaghetti Westerns ? they dealt with ethnic stereotypes of European and Middle Eastern Jews.
Sick of those tired tropes, a group of Israeli moviemakers created an Israeli national movie fund in 1979, hopefully named the "Israeli Fund to Encourage Quality Films."
With meager funding from studios and other private entities, filmmakers rely on public funds. But even with help from the new fund, the industry still floundered for two decades.
In 1995, the government cut public funding for cinema in half, leaving enough money to produce only five films a year. Three years later the industry hit an all-time low: Only 0.3 percent of Israeli moviegoers bought tickets to Hebrew-language cinema.
The national film body took on a new name, the Israel Film Fund, and in 2000 it begged Israel's parliament to save Israeli cinema. It did, boosting the budget to $10 million a year for investment in feature films, mandating that young filmmakers get a chance to make themselves known.
It's what gave Joseph Cedar, the Israeli director of the Oscar-nominated films "Footnote" and "Beaufort," his first big break fresh out of film school: The Israel Film Fund supported his first feature, "Time of Favor," which debuted in 2000.
"We didn't know him, but he had enthusiasm. There was something about his passion," said Katriel Schory, executive director of the national fund. "We took a chance."
In the past, "cinema funds would not support a filmmaker's first feature," said Renen Schorr, founder and director of the Sam Spiegel Film & Television School in Jerusalem. "Today, Israel wants young people to make their first films."
The boost in public funding has dovetailed with investments in Israeli cinema by European and Canadian producers, totaling about $15 million and increasing the number of films Israel puts out annually to nearly 20, according to the Film Fund.
Israel's television industry has also blossomed in recent years. After cable channels and a commercial TV station broke the monopoly and monotony of a lone state-run channel in the early 90s, there was a sudden need for new TV content, spurring competition and creativity among local screenwriters.
Now Hollywood TV executives are taking notice, adapting Israeli shows for American audiences. Showtime's hit thriller "Homeland" is adapted from the Israeli drama "Prisoners of War," the NBC game show "Who's Still Standing" originated in Israel, and other Israeli adaptations are currently in development for American TV.
Despite the surge in budgets, funding is a fraction of public money available for filmmakers in European countries.
While Israel has scored some Academy Award nominations in recent years, it hasn't won. None of the 10 Israeli films that made the best foreign language film shortlist over the years has won the big prize.
Now the focus is on Cedar, director of "Footnote," but he told reporters that the coveted Oscar isn't the only measure of success for a filmmaker.
That is exactly the lesson that his Oscar-nominated film imparts, he said.
"'Footnote' deals with the question of what happens when, while you're living your daily life, a prize is offered, which really takes over your moral reasoning and changes your perspective and sometimes completely destroys your perspective," Cedar said, summarizing the main plot line of his movie.
___
Follow Daniel Estrin: www.twitter.com/danielestrin
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Friday, January 27, 2012
BookPlace DB50: Toshiba Introduces Android-Based Color E-Book Reader
Following Fujitsu, another Japanese electronics maker is ready to sell color e-book readers: Toshiba announced [JP] the so-called BookPlace DB50 today, a 7-Inch device that comes with direct access to big T's BookPlace store (which currently offers around 43,000 different Japanese e-books and magazines). Toshiba says they plan to expand the range of available titles to 100,000 by March this year, the largest in its home market. The store has been available in America since 2010.Source: http://feedproxy.google.com/~r/Techcrunch/~3/UaNxQZuqHjI/
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Zynga called out by company its new game rips off
The opening of Ian Marsh's open letter to Zynga.
Zynga doesn't have the best name around the block, to put it mildly. Various folks across the video game spectrum were quite delighted by news of their recently introduced stock's failure to light Wall Street on fire. Equally satisfying has been reports that their users have stopped playing their offerings in droves.
Much of the animosity stems from the fact that their games are accused of being unoriginal and derivative. Proof can be found in Zynga's latest iOS release "Dream Heights," which strikes a very close resemblance to "Tiny Tower" by NimbleBits, for the same platform. It was actually Apple's pick for best iPhone game of 2011.
This copycatting did not go unnoticed by the makers of the original game, who have voiced their two cents via Twitter. Perhaps the most compelling opinion was shared by David Marsh, one of the co-founders of NimbleBits. He states: "Even when you refuse to go work for Zynga, sometimes you end up doing work for Zynga anyway."
But it is his partner and brother Ian Marsh?who has gotten most of the attention, with side-by-side comparisons in a very tongue in cheek letter addressed to Zynga:
Ian Marsh's open letter to Zynga in its entirety.
The open letter was first highlighted by the iOS-focused gaming blog?Touch Arcade, whichd?also reiterate the very hands-off approach Apple has when it comes blatant clones and other forms of copyright infringement in their App Store. But given how high profile the parties involved are, and especially since Apple itself also anointed "Tiny Tower" with high praise, perhaps Cupertino may be more proactive.
"Dream Heights" is currently available in the Canadian App Store. No word yet on when it'll appear in the U.S. variant, if ever.
Related stories:
Matthew Hawkins is a NYC based game journalist who has also written for EGM, GameSetWatch, Gamasutra, Giant Robot, and numerous others. He also self-publishes his own game culture zine, is part of Attract Mode, and co-hosts of The Fangamer Podcast. You can keep tabs on him via?Twitter,?or his personal home-base,?FORT90.com.
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How to live with the Facebook Timeline
By Rosa Golijan
You can pout and you can shout, but there's no avoiding it: You'll soon be forced to use a new profile page design?? better known as the Timeline???on Facebook. It'll be alright though,?because I'm here to (virtually) hold your hand through this big life change.
Woah! Wait! What is this Timeline thing?
Odds are that you've already?heard about?the Facebook Timeline, but let's have a quick review for the sake of those who might've been on a really long vacation or have a (dangerous) tendency to tune out Facebook-related news.
The Facebook Timeline is a new approach to the profile page. According to Facebook CEO Mark Zuckerberg, it's a way to better present "the story of your life."
When someone looks at your Timeline, he or she will be able to see summaries of the most important events in your personal history ? instead of having to scroll through years of silly status updates. You're able to feature (or hide)?"Stories" ? life?events, images, and other details ??in order to create what you feel is the best representation of your life.
Since your personal history no longer starts with the day you joined Facebook, but the date of your actual birth, you are encouraged to go back and add events which weren't previously on Facebook. Please choose what you enter with absolute care, and bear in mind that what you enter (ahem, place of birth, mother's maiden name) could be used for nefarious purposes.
While a lifelong timeline may seem convenient and logical, our own privacy-minded Helen Popkin said this may be "the ultimate Trojan horse,"?a way for Facebook to squeeze even more personal information out of you by posing as an unrequested but alluring feature.
Oh, and you can also?augment your Timeline by using apps which track books you've read, movies you've watched, music you've listened to, and so on. (Yeah, this can get a bit creepy?? so you'll probably want to fiddle with your privacy settings. More on that later.)
I don't really want this! How do I avoid it?
As I said when we started our journey down the Timeline rabbit hole: You can pout and shout as much as you want, but there's no avoiding Timeline.
As?Paul McDonald, an engineering manager on the Timeline team, explained recently:
Over the next few weeks, everyone will get timeline. When you get timeline, you'll have 7 days to preview what's there now. This gives you a chance to add or hide whatever you want before anyone else sees it. ...?
?You can also choose to publish your timeline at any time during the review period. If you decide to wait, your timeline will go live automatically after seven days. Your new timeline will replace your profile, but all your stories and photos will still be there.
A warning whistle, a seven-day head start, and ... that's it, that's all you're getting. If anyone is trying to convince you that there's a loophole or a way to outsmart Facebook on this particular issue, odds are that he or she is trying to scam you.
Fine. I'll live with this somehow, but can I at least hold on to my privacy?
As Lifehacker's Whitson Gordon points out, the?"one big downside to the Timeline layout is that you can easily see every post you've ever made or received on Facebook. All anyone needs to do is go to a certain year on your profile and click the "All Posts" button."
Yes, that particular downside could lead to quite a bit of embarrassing moments, awkward confrontations, and so on.
Thankfully there are two ways to minimize humiliation. Neither of them is particularly perfect, but they help a bit.
As tedious as it is, you could go through your Timeline and hide (or delete) individual posts. All you have to do is click the little pencil icon on a post and you'll be presented with the different options.
Of course, this process could take forever and a day if you're a particularly active Facebook user. (I told you it wasn't perfect.)
The other action you can take to prevent some embarrassment involves the posts which are visible to the general public or friends of friends. You can change the privacy setting for all of those posts to "friends only" with just one click.?
Live Poll
Are you properly prepared for the arrival of the Timeline?
174337
Wait. What? This is actually happening?
75%
174338
I've been ready for this since it was first announced. Wake me up when there's real news.
9%
174339
I ... I think so. I am, right? Did I forget about something?
12%
174340
Ready? I was born ready (and made myself some custom Timeline cover images later on).
4%
VoteTotal Votes: 1644
You just have to head to the "Privacy Settings" menu, select the "Manage Past Post Visibility" button next to "Limit the Audience for Past Posts." You'll see a little popup which will confirm that you really want to limit the visibility of your old posts and you're done.
But, as?Gordon notes, this particular move "won't hide those posts from your friends, but it will at least keep everyone else on Facebook from being able to browse every post you've ever made public."
Unfortunately that's about all you can do to shelter what little bit or privacy you have left when you're forced to switch over to the Timeline layout. You can?? and should?? be vigilant about what you post in the first place and what sort of state your general privacy settings are in though, of course. (For more details on that, I recommend checking out Lifehacker's "always up-to-date guide to managing your Facebook privacy.")
New York Times columnist Nick Bilton gets creative with his Timeline cover image.
Can I at least make this thing look pretty?
One of the first things you'll notice about the Timeline is that it puts a gigantic photo front and center. This is called the "cover" photo and you're prompted to select one as soon as your profile is converted to this new design. (You can change the cover image as often as you want.)
You can use (or abuse) this feature to make your little corner of the social network look as unique as a snowflake.
Your decorating options include ready-made images ??such as the geeky or intense illustrations artist Sam Spratt made available on BuzzFeed?? or your own creations.
Buzzfeed's Director of Creative Services Tanner Ringerud shows how a profile photo can interact with a cover image on Facebook.
If you're really itching to have a one-of-a-kind image, then the best thing to do is is to brainstorm until you find a way to make the large cover image interact with your profile photo. The only tricky part ? aside from actually coming up with a clever idea ? is that you need to keep the proportions of the images in mind to make sure that everything looks perfect.
So make note that the large cover image is 851 x 315 pixels and that the smaller profile photo is 125 x 125 pixels.
That's really all there is to it?
Yes, that's all you really need to know about the Facebook Timeline??? what it is, why you can't avoid it, how to keep it from embarrassing you, and how to make it look pretty.
Not so bad after all, right?
Now go on and pass this handy-dandy guide on to your confused friends and family members so that you can enjoy your last seven Timeline-free days in peace.
Related stories:
Want more tech news, silly puns, or amusing links? You'll get plenty of all three if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts, or circling her?on?Google+.
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Thursday, January 26, 2012
Country music great Haggard recovering from pneumonia (Reuters)
NASHVILLE, Tenn (Reuters) ? Country singer Merle Haggard, who was admitted to a Georgia hospital last week after illness forced him to cancel a show, was recovering from a host of health issues discovered while he was being treated for pneumonia, his spokeswoman said on Tuesday.
Haggard was admitted to hospital on January 17, when illness forced him to cancel a show in Macon, Georgia, just moments before taking the stage. He later said that being hospitalized "probably saved my life."
The 74-year-old singer, a member of the Country Music Hall of Fame, is recovering from double-pneumonia but was also being treated for a number of serious ailments that doctors discovered while he was hospitalized.
Haggard's pneumonia is "almost completely clear, while he is recovering from three stomach ulcers, the removal of eight polyps from his colon and diverticulitis in his esophagus," which were discovered by the Macon medical staff, according to his Los Angeles-based spokesperson Tresa Redburn.
"He will be back up and running in 30 days," said Redburn, adding that Haggard would be in the hospital for "at least a few more days."
"Thanks to the wonderful people all over the world that prayed their special prayers," Redburn quoted Haggard as saying.
"I'm a new man. Another special thanks to the folks of Macon, Georgia, for their kindness, their intelligence and probably saving my life," he said.
Haggard had to cancel the remainder of his January tour and was planning on beginning his performance schedule again in late February.
With influences ranging from Lefty Frizzell to Bob Wills to Jimmie Rodgers, Haggard is an architect of country music's so-called "Bakersfield Sound." He is best known for songs like "Mama Tried," "Okie from Muskogee" and "The Fightin' Side of Me."
(Reporting By Tim Ghianni; Editing by Cynthia Johnston)
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